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Liu H, Hu X, Li Z, Fa K, Gong H, Ma K, et al

400 Owing to advancements in metabolomics, research on metabolic pathways in cardiovascular diseases is currently extensive, leading to the discovery of more biomarkers

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Dose-escalation decisions in both phases are evaluated by a Safety Review Committee (SRC) , which assesses clinical, pharmacokinetic and safety data according to predefined stopping rules established in the study protocol

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