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Weight loss and anthropometric improvements persisted for up to four years [61]

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Baicalein inhibits interleukin-1beta-induced proliferation of human rheumatoid arthritis fibroblast-like synoviocytes

The diabetes arm REDEFINE 2, run in adults with type 2 diabetes, showed 13.7% weight loss against 3.4% on placebo at 68 weeks a smaller effect, consistent with the pattern that people with diabetes tend to lose somewhat less on these drugs