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PE-22-28: TREK-1 Channel Blockade# PE-22-28 (Gly-Val-Ser-Trp-Gly-Leu-Arg) is a synthetic 7-amino acid peptide derived from spadin, itself an endogenous peptide released by proteolytic processing of sortilin (neurotensin receptor-3)

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Multiple clinical studies have repeatedly demonstrated a significant causal association between high plasma and CSF levels of TMAO and cognitive decline 110,111,115,124126 (Table 6)

The burden of diabetes-associated multiple long-term conditions on years of life spent and lost

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G., Oeltzschner, G., Chan, K