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MASLD and glutathione S-transferases Glutathione-S-transferases (GSTs) play a crucial role in phase II detoxification, as these isoenzymes protect cells against endogenous oxidative stress and exogenous toxins

Free radicals are highly reactive molecules produced by environmental factors or normal metabolism that can damage skin cells and tissues and lead to oxidative stress

Or it could require a process called step therapy, which involves trying (and failing) other drugs, like metformin, phentermine, or bupropion, before moving on to Zepbound

as meal replacements they can support weight maintenance but may require additional fibre or micronutrient supplementation [[131], [132], [133], [134]]