Its nothing short of a scandal how so many patients with severe B12 deficiency are being refused repeat prescriptions for B12 shots
It is important to inform your healthcare professional about allergies to avoid allergic reactions
If vitamin B 12 intake ceases, deficiency would usually not develop for at least 1-2 years, sometimes even longer
[1] As a compounded product, it is not an FDA-approved commercially manufactured drug
studies on patients treated with these substances over a ten year period
[1] [13] When B12 levels are borderline or clinical suspicion remains high despite normal B12, additional tests include: Holotranscobalamin (active B12) , which may be more sensitive in early or borderline deficiency Methylmalonic acid (MMA) and homocysteine levels, which become elevated in functional B12 deficiency (note that MMA is also elevated in renal impairment, and homocysteine rises in folate and B6 deficiency) Full blood count to identify macrocytic anaemia (elevated mean cell volume) Blood film examination may show hypersegmented neutrophils and megaloblastic changes Serum folate should be checked concurrently, as deficiencies often coexist Investigating the underlying cause is essential for appropriate management
