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(4 June 2022)

Current clinical evidence for possible antidepressant effects of GLP-1R agonists Depression is often comorbid with metabolic disorders such as T2DM and obesity and many antidiabetic drugs, which often display neuroprotective and immunomodulatory effect, have demonstrated antidepressant properties in clinical trials

doi: 10.1016/j.amjmed.2009.09.008

in human testes [44, 45], has the potential to generate free radicals in a calcium-dependent manner, as originally described by Aitken and Clarkson [25]

The PMC review of Contrave trials shows weight loss ranged from 3.7% to 8.1% depending on the study protocol

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