PLoS One 16 (2), e0245939
Choosing the Right GHRP Maximum GH amplitude: Hexarelin but accept higher side effects and desensitization risk Balanced potency/tolerability: GHRP-2 moderate GH with manageable side effects Appetite stimulation priority: GHRP-6 strong hunger drive, useful in wasting models Cleanest side-effect profile: Ipamorelin no appetite, cortisol, or prolactin effects Cardiac research: Hexarelin the only GHRP with robust cardiovascular data An oral secretagogue alternative is MK-677, which also targets GHSR-1a but with a much longer half-life (~24 hours) and oral bioavailability
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