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Mild-to-moderate nausea during week 12 is expected and usually resolves within 35 weeks as your digestive system adapts

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For many people, that means using a lower, carefully adjusted dose to help manage appetite and prevent regain

Sex, ethnicity, and metabolic status may all influence this relationship

In a study of 1310 French patients with diabetes who were hospitalized for myocardial infarction, in-hospital mortality rates were significantly lower in patients previously treated with sulfonylureas compared with other oral medications, insulin, or no medication (3.9%, 6.4%, 9.4%, and 8.4%, respectively, odds ratio for patients receiving sulfonylureas before admission compared with no sulfonylureas 0.50, 95% CI: 0.270.94) [44]