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The question has shifted from "is it too expensive to cover GLP-1?" to "is it too expensive not to?" As clinical data accumulates showing that GLP-1 medications reduce the incidence and severity of the most expensive chronic diseases, payers are recognizing that proactive treatment of obesity saves money compared to treating its downstream consequences

Biochemistry 33: 3532-3539, 1994

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These usually improve as your body adjusts

The most common side effects of tirzepatide are gastrointestinal in nature, including nausea, constipation, and occasional diarrhea, and these typically improve as the body adjusts during the early weeks of dose titration

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