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[2] Exposure to nitrous oxide (including recreational use) can cause functional B12 deficiency and worsen neurological manifestations

doi: 10.1093/jcag/gwac035

In a 24-week extension study, the treatment response rates for 5 mg, 10 mg, and 20 mg doses were 40%, 50%, and 45%, respectively, compared to a 25% response rate for the placebo

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doi:10.1371/journal.pone.0074381 11

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