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(2025, Olympia) Safety Concerns Compounded GLP1s lack the FDA approval that commercially manufactured drugs undergo, meaning they may not have been subjected to the same rigorous testing for safety and efficacy

Example: 200 lb person = 240-300g protein daily Carbohydrates: Strategic timing IGF-1's glucose-lowering effects require careful carb management: Pre-workout: 40-60g carbs (fuel training) Post-injection: 30-50g fast carbs (prevent hypoglycemia) Post-workout meal: 60-80g carbs + protein (maximize nutrient uptake) Throughout day: 200-300g total depending on body size Fats: Don't neglect Supports hormone production 0.4-0.5g per lb body weight Focus on omega-3s (fish oil, salmon, walnuts) Hydration: Critical IGF-1 increases metabolic demands and protein synthesis, both water-intensive processes

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Appetite suppression patterns begin to establish, and early metabolic changes may become measurable

10.1111/j.1471-4159.2007.04483.x J Neurochem