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While fatty acylation preserves receptor interaction and facilitates tissue penetration, its pharmacokinetics may be influenced by endogenous albumin levels, and long-term use could potentially trigger immune responses due to the lipid moieties

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Present study showed significantly elevated levels of lipid peroxide (MDA) in patients at risk for CAD

doi: 10.1038/s41418-020-0528-x 111 FangYChenXTanQZhouHXuJGuQ

The WHO review concluded: GLP-1 medications are clinically effective for weight reduction and metabolic improvement

[13] These are typical GLP-1 side effects and are usually mild to moderate in severity