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SCA is manifested as the result of the presence of an autosomal recessive allele, which is found on the short arm of chromosome 11p15.5 [14]
These activated intermediates are then incorporated into membrane phosphatidylethanolamines (PEs) by lysophosphatidylcholine acyltransferase 3 (LPCAT3), generating the highly oxidizable species AA-PE and AdA-PE ( The intracellular GSH-GPX4 axis constitutes the core antioxidant defense mechanism against ferroptosis
however undergoing general anesthesia comes with significant risks
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