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Rotating injection sites among recommended areas (abdomen, thigh, upper arm), cleansing the skin before injection, and avoiding areas with visible blood vessels, inflammation, infection, or scarring can help minimize these reactions

The frequency and severity of gastrointestinal effects represent a significant clinical consideration

For a full list of possible side effects, and other important safety information, please reference the Mayo Clinics list of Semaglutide side effects

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When used to treat diabetes, GLP-1s are used alongside other medications , such as metformin, which helps the liver produce less glucose

31.5%), 10% (69.1% vs