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These findings suggest that DCA- or nutrient-induced GLP-1 secretion was inhibited by pasireotide via SSTRs-Gi-dependent inhibition of cAMP levels

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[14] Urgent referral should also be considered for those under 50 with rectal bleeding plus other concerning features, those aged 40+ with unexplained weight loss and abdominal pain, and those aged 60+ with change in bowel habit or iron-deficiency anaemia