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A vitamin B complex injection does not replace vitamin B12 when deficiency is present

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Common side effects include, but may not be limited to: pain or redness at the injection site mild diarrhea pruritus (itching) increased swelling joint pain dizziness headache nervousness or anxiety Serious side effects may include: allergic reactions peripheral vascular thrombosis hypokalemia (low potassium levels) pulmonary edema (fluid build-up around or in the lungs) thrombocytosis congestive heart failure There have been reports of anaphylactic shock and death after the parenteral administration of vitamin B12

All published rodent metabolic studies used subcutaneous injection as the exclusive route

B12 deficiency can affect individuals of all ages, but most particularly elderly individuals, as older adults are more likely to have decreased stomach acid production, which is necessary for B12 absorption and they easily develop vitamin B12 deficiency