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Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

Garibaldi C, et al

[18] Los afroamericanos con lupus tambin han demostrado tener niveles reducidos de glutatin en sus linfocitos T

J Am Geriatr Soc 2019;00:1-21

There is no recommendation to use this treatment for an extended period of time