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Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

Provider familiarity with published efficacy data is crucial when selecting between them

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Crucially, comprehensive drug safety testing in mice indicated no significant adverse effects on myocardial, liver, or renal function markers after 30 days of treatment, suggesting a favorable safety profile [2]

So we can actually see in our data the value of a lifestyle intervention on top of the drugs

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