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Chenglai Xia, [email protected] These authors have contributed equally to this work This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Discuss potential side effects and your tolerance for them

Missing a dose entirely may cause appetite to return within days as semaglutide levels drop, potentially triggering overeating or cravings

Whether loose skin will tighten on its own depends primarily on patient age, how long the skin was stretched, how much weight was lost, and how quickly it happened

doi: 10.1111/vcp.13381

Why Temperature Matters for GLP-1 Medications To understand why refrigeration is so critical, it helps to know what these medications actually are