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This triggers a pulsatile release of endogenous growth hormone (GH), which is physiologically important because it mimics the natural GH secretion pattern rather than flooding the body with supraphysiological levels
PMID: 29752673 22
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However, they differ in a key way: tirzepatide is a dual agonist (GLP-1 and GIP), while retatrutide is a triple agonist (GLP-1, GIP, and GCG)
Doctors typically The list below includes other drugs that may interact with Wegovy
Once those receptors are filled by a medication like tirzepatide, there is nowhere for the semaglutide to go
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