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doi: 10.2174/1386207324666210705114058 286 ChenMWangSChenYShenHChenLDingLet al

As a synthetic fragment of human GH residues 176-191, it allows researchers to study the metabolic arm of GH signalling independently of IGF-1 pathway activation

Most considerations of non-animal alternatives for skin irritation/sensitization testing tend to examine a single aspect of the process (e.g., chemical reactivity, epidermal bioavailability, dendritic cell responses)

Kojic acid can be combined with hydroquinone for enhanced effects, though this increases irritation risk

doi: 10.3389/fphar.2021.627533 Received 09 November 2020 Accepted 03 February 2021 Published 29 June 2021 Volume 12 - 2021 Edited by Gabor Varga, Semmelweis University, Hungary Reviewed by Alexandra Mik, University of Pcs, Hungary Zoltn S

MuSC Proliferation In aged skeletal muscle, NNMT overexpression is linked to impaired NAD+ salvage, dysregulated SIRT1 activity, and increased muscle stem cell (MuSC) senescence