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Circadian rhythm sleep disorders such as delayed sleep phase disorder (DSPD) and advanced sleep phase disorder (ASPD) are often associated with depression 60,61

Hernandez-Rey said it is strongly recommended to stop GLP-1 medications at least one to two months before attempting pregnancy to avoid potential risks to a fetus

The GLP-1 system doesn't reset immediately after stopping the drug, meaning patients may experience persistent nausea, altered food preferences, or loss of hunger cues for months

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