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Dichloroacetate Dichloroacetate (DCA), a product of water chlorination, is considered for the treatment of several disorders including genetic mitochondrial diseases and some hyperproliferative conditions 82

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Amphetamine increases the concentration of dopamine in the synaptic cleft by entering the presynaptic neuron by diffusing across the neuronal membrane directly or through DAT, competitive reuptake inhibition at the transporter, and finally, the reversal of dopamine transport through DAT (i.e., dopamine efflux) [159,160,161]