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Diagnosis is typically based on Thyroid-Stimulating Hormone (TSH) levels: subclinical hypothyroidism is characterized by elevated TSH with normal triiodothyronine (T3) and thyroxine (T4), and overt cases showed elevated TSH levels with low T3 and T4

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The skin penetration problem A critical issue for topical GHK-Cu is whether the peptide actually reaches its target cells

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