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When calorie intake is reduced, as it often is with GLP-1 medications, protein needs may increase

Compounded medications are not FDA-approved as a class (unlike branded versions), but are permitted under 503A licensing

Laparoscopic adjustable gastric banding with liraglutide in adults with obesity and type 2 diabetes (GLIDE): a pilot randomised placebo controlled trial

Kristensen et al., 2019

Always review FDA-approved prescribing information and discuss risks, alternatives, and eligibility with a qualified healthcare professional before starting any treatment

Then there is the glucagon receptor, which is unique to retatrutide among the current generation of weight loss peptides