Purchasing preferences also shifted, with a 10.1% decline in snack purchases, along with similar decreases for sweets, baked goods, and cookies
For type 2 diabetes patients with significant insulin resistance and obesity, tirzepatide may address the root metabolic dysfunction in ways that exogenous insulin cannot
Research on pathomechanisms in manifestation and progression of HFpEF in humans is currently hampered by many obstacles (difficult diagnosis of early progression stages, inaccessibility of tissue samples, heterogeneity of cohorts)
Mitochondrial dysregulation within the liver has been found to be a hallmark of MAFLD
For researchers developing oral formulations of GLP-1RAs, including oral semaglutide, the fact that absorption takes place in the stomach presents a challenge
Multi-omics studies revealed that SARS-CoV-2 infection provokes significant changes in numerous metabolites including those impacting on virus propagation (one-carbon metabolism) and GSH synthesis (amino acids glutamic acid, cysteine and glycine) that could be used as early prognosis biomarkers in COVID-19 at diagnose to predict severe COVID-19 and LONG COVID (Doan et al., 2021
