The imbalance of the redox status mediated by folate deficiency or methionine load has been characterized by various indices of oxidation such as increases in end-products of lipid oxidation (conjugated dienes, hydroperoxides, and thiobarbituric acid reactive substances), changes in the fatty acid composition with decreased polyunsaturated fatty acids (mostly n-3 fatty acids), and a lower antioxidant defense, as demonstrated using the free radical-mediated erythrocyte hemolysis test described in Durand and Blache (1996) and in Prost (1992)
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CL Answer Do any supplements help reduce menstrual pain or symptoms of premenstrual syndrome (PMS)
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However, this association does not imply causationelevated B12 often serves as a biomarker for serious underlying disease rather than being directly harmful