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2 A separate 2-week RCT testing three GlyNAC dose levels in 114 healthy older adults found good tolerability but no significant improvement in the primary endpoint (GSH:GSSG ratio) in the full study population, highlighting that responses may depend on baseline oxidative stress levels and study duration

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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Wu SS, Sun F, Zhan SY

The animal studies, while promising, cannot fully predict human responses