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( 10.1016/j.molmet.2019.09.010) [DOI] [PMC free article] [PubMed] [Google Scholar] 3.Nauck MA, Heimesaat MM, Behle K, Holst JJ, Nauck MS, Ritzel R, Hfner M, Schmiegel WH

These results suggest there is no excess cardiovascular risk with tirzepatide and are consistent with the improvements of numerous surrogate markers of cardiovascular health, including weight reduction, glycemic control with less hypoglycemia, blood pressure reduction, and improvements in the lipid profile

95% CI 0.78 1.067

Mol Metab 2019

The medications are quite expensive and insurance will often not cover them after a year

Clinical trial data demonstrates that most patients who experience nausea or vomiting find these symptoms are transient and mild to moderate in severity