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P4 plays a pivotal role in triggering polyploidization and the differentiation of the elongated fibroblastic stromal cells into rounded secreting decidual cells, thereby initiating the secretion of stromal factors such as prolactin (PRL) and insulin-like growth factor binding protein 1 (IGFBP1) to establish an immunotolerant and nutrient-rich environment essential for successful embryo implantation and pregnancy maintenance [4, 5]
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Other drugs, including certain antidepressants, diuretics, and antihistamines, may also impact test results
However, there was no significant effect seen on fasting blood sugar (FBS), triglyceride (TG), and high-density lipoprotein-cholesterol (HDLc) when comparing the intervention and placebo groups
There were 25 overlapping DEPs between HFD/Sema and NCD/HFD in Venn diagram, including 12 up-regulated and 13 down-regulated proteins ( Figure 4C )
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