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In research settings, GHK-Cu is used to investigate copper-dependent tissue remodeling and repair pathways, including extracellular matrix regulation (e.g., collagen/proteoglycan balance and matrix metalloproteinase activity) and wound-repair signaling in cellular and tissue models

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Rice DC, Stevens C, Forster K, Vaporciyan AA, Walsh GL, Swisher SG , Hofstetter WL, Mehran RJ, Roth JA, Liao Z, and Smythe WR