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Read the guide Important safety information: Phentermine is a Schedule IV controlled substance approved for short-term use (typically 12 weeks or less)

IL-1 and TNF- stimulate chondrocytes and synovial cells to secrete MMP-1, MMP-3, and MMP-13, which degrade collagen and proteoglycans in the cartilage matrix, worsening cartilage damage (150, 151)

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