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Headaches are a possible side effect of GLP-1, although not everyone experiences them
Seek urgent medical attention for sudden severe headache, headache with fever or visual changes, persistent vomiting, or symptoms suggesting serious complications
There are now three GLP-1RA drugs approved in multiple countries [see Table 1] for chronic weight management, all of which are administered as injections: Wegovy (active substance semaglutide) and Saxenda (active substance liraglutide) from Novo Nordisk, and Mounjaro/Zepbound 1 (active substance tirzepatide) from Eli Lilly the latter being the first dual receptor agonist 2 drug approved
Some patients take them long-term for maintenance, while others taper off under medical guidance after achieving goals
Both can cause it to stop working right