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The two most common culprits are: Iron: An iron deficiency can lead to anaemia, with profound fatigue, weakness, and shortness of breath being hallmark symptoms

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Data availability All sequencing profiles, including RNA-seq and miRNA-seq, were uploaded to GEO (GSE205494, GSE205579)

Campochiaro PA, Iftikhar M, Hafiz G, Akhlaq A, Tsai G, Wehling D, Lu LL, Wall GM, Singh MS, Kong XR