Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism
The goal is sustained weight management, not temporary cosmetic change
Diabetic neuropathy mainly comprises distal symmetric polyneuropathy, leading to sensory loss, pain, and motor dysfunction, and can result in diabetic foot ulcers requiring lower-limb amputations
FUNDING None NOTES We thank our lab members for support and discussion
PMID: 40554718 Walker AF, et al
An accumulation of sometimes controversial data has opened the debate as to whether metformins favorable effects extend beyond its anti-hyperglycemic actions and include a role as an anti-aging drug that enhances healthspan and extends lifespan thus raising the hope that it could be the Fountain of Youth (26, 27, 29, 3642)