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Expression of Gipr in dorsal root ganglion (n = 9 WT, n = 6 KO) (c) , hypothalamus (n = 12 WT, n = 10 KO) (d) , hindbrain (n = 12 each group) (e) , sciatic nerve (n = 12 WT, n = 10 KO) (f) , eWAT (n = 12 each group) (g) and pancreas (n = 12 each group) (h) of 45-week old male mice Chow-fed Per-Cre + Gipr wt/wt (WT) and Per-Cre + Gipr flx/flx (KO) mice

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Iron supplements: These are notorious GI irritants that cause nausea, constipation, and can worsen heartburn