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Healthcare providers typically stress sticking to the initial dosing schedule during this time

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To optimize effective absorption, patients are required to adhere to complicated dosing conditions of taking the drug in a fasting state (at least 30 minutes before any food intake) with no more than 4 ounces (approximately 120 mL) of plain water

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In laboratory practice, this means that after the first collection, the material does not automatically become resistant to contamination

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