We found here that agonist trafficking properties, as well as insulin secretion, mirrored -arrestin recruitment propensity, contrasting with some 14,33 (but not all 34 ) previous work suggesting that -arrestins do not impact GLP-1R trafficking 14,34,35 , as well as reports of coupling of GLP-1R to insulin secretion via -arrestin-1 14 (although not -arrestin-2 60 )
Fischer GM, Guerrieri RA, Hu Q, Carapeto FC, Joon AY, Gopal VY, Knighton B, Deng W, Haydu LE, Gershenwald JE, Lazar AJ, Tetzlaff MT, Davies MA
I have not recommended it to anyone
Xie X, Yang S, Deng S, et al
Mind you these kits are quite expensive
The American College of Gastroenterology guidelines for IBS management emphasize the importance of comprehensive medication counseling and established follow-up plans for patients with functional gastrointestinal disorders