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The molecular responses observed vary with receptor subtype, concentration, exposure time, and experimental model, and PT141 is used to characterise melanocortinreceptor signalling rather than to infer defined biological or physiological outcomes

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doi: 10.1111/ajco.70036 143 GaoJWangWQPeiQLordMSYuHJ

made in-house) were incubated overnight at 4C, followed by staining with donkey anti-rabbit Alexa Fluor 488 Plus antibody (1:1,000

In some embodiments, the otic formulation or composition comprises between about 0.10% to about 3% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof