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Among the key issues that may answer the question of whether aptamers can remain intact and functional within biological systems, stability is the cornerstone challenge for their successful clinical translation

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In an I/R-mediated myocardial injury model, pretreatment with Tan IIA activated the GSH system by increasing Nrf2 expression [154]

Insulin resistance in skeletal muscle Insulin-stimulated glucose consumption is largely conducted in skeletal muscle, and thus, muscular insulin resistance could affect whole-body metabolism [28]

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