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In contrast to EAE where the primary stimulus is immune upregulation in the presence of extrinsic myelin antigens, the CAE model illustrates that MS-like pathology can also be generated by an upstream intrinsic myelin injury, releasing antigens which secondarily trigger white matter inflammation in an immune-predisposed host

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While these treatments can be effective in promoting weight loss, it's important to be aware of the potential side effects and to discuss your options with your doctor

This survey will apply to all hospitals paid under the OPPS, which for purposes of our burden calculations we estimated to be 3,500 hospitals in the CY 2026 OPPS/ASC proposed rule

The basal ganglia has been the favored DBS target to date because of the fact that link(s) between activity changes in specific basal ganglia circuits and movement disorders are relatively well-established