Dumont C, Beloqui A, Miolane C, Bourgeois S, Prat V, Fessi H, Jannin V
In addition to aiding in weight reduction, semaglutide also helps lower blood sugar, making it especially beneficial for individuals with diabetes
And the inconsistent bioavailability of oral formulations means some percentage of users are paying for convenience while getting subtherapeutic blood levels
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You might develop various gastrointestinal side effects, including gas, bloating, indigestion, nausea, or irregular bowel movements
Below is an overview of how the two compare: Mechanism of Action: Retatrutide: Triple agonist (GLP-1, GIP, glucagon) Zepbound: Dual agonist (GLP-1, GIP) Developer: Retatrutide: Eli Lilly and Company (investigational) Zepbound: Eli Lilly and Company (approved) Regulatory Status: Retatrutide: Phase III clinical development Zepbound: FDA-approved for obesity, obstructive sleep apnea Weight Loss Efficacy: Retatrutide: Up to ~28.7% (68 weeks