The results showed that 11 patients experienced mild nausea (n=6) and vomiting (n=5), with no serious adverse reactions or deaths
Hormone Research in Pdiatrics
In clinical trials, retatrutide at higher doses showed mean heart rate increases that exceeded those seen with tirzepatide
Moving too quickly to high doses wastes product if you respond well to lower amounts, and offers no additional safety buffer if issues arise
There was an increased risk of gastrointestinal disorders, hypotension, syncope, arthritic disorders, nephrolithiasis, interstitial nephritis and drug-induced pancreatitis associated with GLP-1RA use compared to usual care, the researchers concluded
Gut-brain axis and addictive disorders: a review with focus on alcohol and drugs of abuse