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On this basis, we conclude that metformin should not be seen as a quick fix panacea for aging at the expense of non-pharmacologic interventions such as diet, exercise, and related lifestyle changes
For example, conditions such as thyroid disorders , polycystic ovary syndrome (PCOS) , and insulin resistance can affect how well these medications manage appetite and metabolism
Depending on the species, the half-life is approximately 1 to 2 min (13)
While these drugs show initial promise, the data suggests they may be treating symptoms rather than addressing root causes of metabolic dysfunction
[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Massollo M, Marini C, Brignone M, et al
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