For comparison, semaglutide trials showed roughly 15% weight reduction over similar timeframes, and even tirzepatide topped out around 22% in its best-performing cohort
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There is also growing interest in whether GLP-1 medications may help with nicotine dependence, binge eating disorder, and other compulsive reward-driven behaviors, says Anton
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Loos, a professor at the University of Copenhagen and affiliated with a research center supported by the Novo Nordisk Foundation (the maker of Wegovy and Ozempic), noted, "The current model explains only 25% of the variability, and further research is needed to uncover the remaining 75%." However, she also expressed optimism, stating, "By combining genetic and clinical information, the era of personalized medicine, where we can select the best drug for each patient, may be upon us."
