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RNA helicase A interacts with RISC in human cells and functions in RISC loading

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Excessive deposition of extracellular matrix (ECM) and lung tissue remodelling is a central characteristic of fibrotic disorders and the ECM has been attributed a key role in the progressive nature of IPF 23

In the LEADER trial, over 9,340 patients with type 2 diabetes and high cardiovascular disease risk underwent randomization to liraglutide or placebo and were followed for a median of 3.8 years resulting in a 13% risk reduction in a combined endpoint of death from cardiovascular cause, nonfatal myocardial infarction, or nonfatal stroke [46]

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