retatrutide phase 2 trial type 2 diabetes weight loss 2024 Retatrutide, a TRIPLE agonist (GLP1, GIP, glucagon), just released results demonstrating 25% in half of people with #obesity. This amount of weight loss has not been accomplished Effects of retatrutide on body

However, semaglutide has cardiovascular outcome data (the SELECT trial) that tirzepatide does not yet have from a completed dedicated outcomes trial

The progression is straightforward: semaglutide targets one receptor pathway and achieves approximately 1517% weight reduction in trials

My doctor said Id lost too much muscle

The weekly dosing convenience is one reason GLP-1 medications have gained such widespread adoption, with many patients preferring one injection per week to the daily injections that insulin protocols require

Over the counter antihistamines like diphenhydramine (Benadryl) or cetirizine (Zyrtec) can reduce itching and minor allergic type reactions at injection sites

..I wrote one-third of the LessWrong posts I've ever written in the last month [3]