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In further or alternative embodiments, the otic gel formulations are capable of being administered on or near the round window membrane via intratympanic injection

Peer review Peer review information Nature Communications thanks David Lythgoe, Christopher Pittenger and Odile van den Heuvel for their contribution to the peer review of this work

Starting at lower frequency and concentration, then gradually increasing, prevents this problem almost entirely

Dilated pupils, light sensitivity, and insomnia make it harder to rest, and the lack of rest amplifies everything else

In that light, intake of Se could be beneficial for children with DS as a part of the immune response to bacterial antigens [89]

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