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They concurrently suppress NF-Bdriven transcription of pro-inflammatory genes such as *Tnfa* and *Il1b*, and modulate bile acid and lipid homeostasis through activation of the farnesoid X receptor (FXR)small heterodimer partner (SHP) axis

Our study confirmed that SFN can be effective against cutaneous inflammation in an IMQ-induced psoriatic mouse model, consistent with previous findings of its therapeutic effects in chronic inflammatory diseases such as inflammatory bowel disease, respiratory diseases, and rheumatoid arthritis [35]

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Switch to heam iron There are two main types of iron: Haem iron: a dietary iron found only in animal tissue, such as meat, seafood, and poultry