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**Neurological Disorders:** Supportive treatment in certain neurological disorders associated with vitamin B12 deficiency, such as peripheral neuropathy

That's a meaningful distinction when you consider what happens the moment you stop using the drug and blood flow returns to normal

When deficient, replacing it often restores appetite and energy and prevents longer-term harm

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The combination may reduce gut inflammation on multiple levels, including systemically, via cytokine signaling, and through modulation of the intestinal immune response